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Database I: Genetic Tests for Cancer: Database of genetic tests currently available

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2. Test (by major types of cancer)
Name Test Type Breast Prostate Lung Colorectal Pancreas Ovarian Esophagus Liver Lymphoma Leukemia
Acid phosphatase, total and prostatic ICMA,spectphoto   x                
Adrenocorticotropic hormone ICMA     x   x          
Alpha fetoprotein ICMA     x x x     x    
AML1/ETO translocation PCR                   x
B-cell gene rearrangement PCR                 x  
BCL-1/JH gene rearrangement PCR                 x  
BCL-2 translocation PCR                 x  
BCR/ABL gene rearrangement PCR, FISH                   x
Beta human chorionic gonadotropin ICMA     x x   x   x    
Beta-2 microglobulin ICMA                 x  
Bladder tumor antigen Cytology, EIA                    
BRCA Analysis PCR x       x x        
Calcitonin ICMA                    
Cancer antigen 125 MEIA, ICMA x   x x x x        
Cancer antigen 15-3 ICMA x                  
Cancer antigen 19-9 EIA       x x     x    
Cancer antigen 27.29 ICMA x   x   x x   x    
Carcinoembryonic antigen ICMA x   x x x x        
Cathepsin D IHC x                  
CBFB/MYH11 fusion protein PCR                   x
CD 117, c-kit IHC                    
CD 20 Flow cytometry                 x  
CD 25 IHC,flow cytometry                 x  
CD 33 Flow cytometry                   x
CD 52 Flow cytometry                   x
Chromosome 18q assay PCR       x            
Colaris PCR       x            
Colaris AP PCR       x            
Cyclin-D1 IHC                 x  
E-cadherin IHC   x                
Epidermal growth factor receptor IHC x x x x            
Estrogen/progesterone receptor IHC x                  
Fecal globin IHC       x            
FLT 3 mutation PCR                   x
HER-2/neu IHC, FISH, EIA x         x        
5-HIAA Liquid chromatography                    
Human papillomavius hybrid capture DNA probe                    
IgVH mutation analysis PCR                   x
Immunocyt Cytology, ICC                    
Kappa/lambda light chain IHC                 x  
LAP Enzyme assay         x          
Lipid associated sialic acid Spectrophotometry x   x x x x   x x x
Melaris PCR         x          
MIB-1 antibody IHC x               x  
Micrometastasis detection IHC x                  
Microsatellite instability PCR       x            
MLH1, MSH2, MSH6 mutations PCR       x            
Neuron specific enolase RIA     x   x          
Nuclear matrix proteins EIA                    
Oncotype Dx PCR x                  
p53 tumor suppressor gene IHC x x   x            
PML/RARA translocation PCR                   x
PreGen-26 PCR       x            
PreGen-Plus PCR       x            
Prostate-specific antigen ICMA, IRMA, EIA   x                
T-cell recepter gene rearrangment PCR                 x  
TEL/AML1 gene fusion FISH                   x
Thyroglobulin ICMA                    
Tumor antigen 90 immune complex EIA                    
Urokinase plasminogen activator EIA x                  
Urovysion FISH                    
ZAP-70 Flow cytometry                   x

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