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Appendix B Table.  Quality of Included Studies

#

First Author, Year

Quality 1*

Quality 2*

Quality 3*

Quality 4*

Quality 5*

Quality 6*

Total Score

1.

Alexanian, 2002111

N

Y

N

Unk

Y

N/A

2/5

2.

Alexanian, 200364

Unk

N

Unk

Unk

Y

N

1/6

3.

Anagnostopoulos, 200368

Unk

N

Unk

Unk

Y

N

1/6

4.

Badros, 2002115

Y

N

Unk

Unk

Y

N/A

2/5

5.

Barlogie, 200143

Y

Y

N

Y

Y

N

4/6

6.

Barlogie, 2002109

Unk

N

Unk

Y

Y

N

2/6

7.

Bernardeschi, 200469

Unk

N

N

Y

Y

N/A

2/5

8.

Biagi, 200192

N

Y

N

N

Y

N

1/6

9.

Bowcock, 2002116

Unk

N

Unk

Unk

No

N/A

0/5

10.

Ciepluch, 200293

N

Y

N

Unk

N

N/A

1/5

11.

Corso, 200244

N

N

Unk

Unk

Unk

N/A

0/5

12.

Dimopoulos, 200170

Y

Y

N

N

Y

N/A

3/5

13.

Dimopoulos, 200494

Y

Y

N

Unk

Y

N/A

3/5

14.

Dmoszynska, 2002128

Y

N

N

Y

Y

N/A

3/5

15.

Fahdi, 2004117

Y

Y

Unk

Y

Y

N

4/6

16.

Garcia-Sanz, 200495

Y

Y

N

Y

Y

N/A

4/5

17.

Hall, 2003118

Unk

N

Unk

Unk

Yes

N/A

1/5

18.

Hattori, 200445

Y

Y

Y

Unk

Y

N/A

4/5

19.

Hus, 200146

Y

Y

N

Unk

Y

N

3/6

20.

Johnston, 200247

N

Y

N

Y

Y

N/A

3/5

21.

Juliusson, 200048

N

N

N

Unk

Y

N/A

1/5

22.

Kasper, 200497

N

N

N

Y

Y

N/A

2/5

23.

Kees, 200349

N

N

N

Y

Y

N

2/6

24.

Kropff, 200398

Y

Y

Y

Y

Y

N/A

5/5

25.

Kumar, 200351

Y

Y

N

Y

Y

N/A

4/5

26.

Lee, 200321

Y

Y

Y

Y

N

N/A

4/5

27.

Mileshkin, Biagi, et al., 200399

Y

Y

N

Y

Y

Y

5/6

28.

Mileshkin, Prince, et al., 2003127

Y

Y

N

Y

Y

N

4/6

29.

Myers, 2000, 2001, and 200271-73

Unk

N

Unk

Y

Y

N/A

2/5

30.

31.

32.

Neben, Moehler, Kraemer, et al., 2001129

Y

N

N

Y

Y

N

3/6

33.

Neben, Moehler, Egerer, et al., 200152

Y

N

N

Y

Y

N

3/6

34.

Neben, Moehler, et al., 2002134

Y

Y

Unk

Y

Y

N

4/6

35.

Neben, Mytilineos, et al., 2002131

Y

N

N

Y

Y

N

3/6 (presumed from 52)

36.

Offidani, Corvatta, Marconi, Malerba, et al., 2004101

Unk

N

N

Unk

N

N

0/6

37.

Offidani, Corvatta, Marconi, Olivieri, et al., 2004102

Y

Y

Y

Y

Y

Y

6/6

38.

Palumbo, 200174

Unk

N

Unk

Y

Y

N/A

2/5

39.

Palumbo, 200475

Y

Y

Y

Y

Y

Y

6/6

40.

Rajkumar, 200053

Y

Y

N

Unk

Y

N/A

3/5

41.

Rajkumar, 200141

Y

Y

Y

N

Y

N/A

4/5

42.

Rajkumar, 200265

Y

Y

Y

Unk

Y

N/A

4/5

43.

Rajkumar, 200342

Y

Y

N

N

Y

N/A

3/5

44.

Richardson, 200454

Y

Y

Unk

N

Y

N/A

3/5

45.

Schey, 200355

Y

Y

Unk

Y

Y

N/A

4/5

46.

Schutt, 200587

Y

Y

Y

Y

Y

N/A

5/5

47.

Shaughnessy, 2003133

Unk

N

Unk

Y

Y

N

2/6

48.

Singhal, 199935

Y

Y

Y

Y

Y

N/A

5/5

49.

Thompson, 2003130

Unk

N

Unk

Unk

Y

N

1/6

50.

Tosi, 200156

Y

Y

N

N

Y

N/A

3/5

51.

Tosi, 200257

Y

N

N

N

Y

N/A

2/5

52.

Tosi, 2004135

Y

Y

N

Y

Y

N/A

4/5

53.

Tosi, 2005121

Y

Y

N

Y

Y

N

4/6

54.

Waage, 200458

Y

Y

Unk

Y

Y

N/A

4/5

55.

Weber, 200367

Y

N

Unk

Y

Y

N

3/6

56.

Yakoub-Agha, 200059

Y

Y

Y

N

Y

N/A

4/5

57.

Yakoub-Agha, 200260

Y

Y

Y

Y

Y

Y

6/6

58.

Zangari, 2001122

Unk

N

Unk

Unk

N

N/A

0/5

59.

Zangari, Saghafifar, et al., 2002123

Unk

N

Unk

Unk

N

N

0/6

60.

Zangari, Siegel, et al., 2002124

Unk

N

N

Y

Y

N

2/6

61.

Zangari, 2004126

Y

Y

Y

Y

Y

Y

6/6

62.

Zervas, 200488

Y

Y

N

N

Y

N/A

3/5

Notes:

  • Quality Question 1. Is the study based on a representative sample from a relevant population?
  • Quality Question 2. Are the criteria for inclusion explicit?
  • Quality Question 3. Did all individuals enter the survey at a similar point in disease progression?
  • Quality Question 4. Was followup long enough for important events to occur?
  • Quality Question 5. Were outcomes assessed using objective criteria or was blinding used?
  • Quality Question 6. If comparisons of sub-series, was there a sufficient description of the series and distribution of prognostic factors?

Abbreviations: N=No; Y=Yes; N/A=not applicable; Unk=unknown

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