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Table 14a. Predictors of Disease Response or Survival—Thalidomide Dosage and Response Factors That Correlate With Overall Response to Thalidomide: Summary
Prognostic Factor |
Number of studies indicating significant correlation with tumor response/ total number of studies indicating factor |
Number
of studies indicating significant correlation with survival/ total number
of studies indicating factor |
| Cumulative 3-mo Thal dosage
|
Some correlation with response=1/2
(Yakoub-Agha, 200260) No correlation=1/2
(Neben, Moehler, et al., 2002134)
|
Correlation with survival=2/2
(Neben, Moehler, et al., 2002134; Yakoub-Agha, 200260)
|
| Change in paraprotein levels
|
Correlation with response=1/1
(Schey, 200355)
|
|
| Relationship between paraprotein response and BM response
|
Correlation with response=1/1
(Singhal, 199935)
|
|
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