CME module offered on in-hospital off-label uses of recombinant factor VIIa
Research Activities, April 2011, No. 368
A continuing medical education (CME) module offered by AHRQ's Effective Health Care Program, Comparative Effectiveness of In-Hospital Off-Label Use of Recombinant Factor VIIa vs. Usual Care, offers an American Medical Association PRA Category 1 Credit™ based on a comparative study of the utilization and effectiveness of the use of recombinant factor VIIa (rFVIIa). The study found that current evidence does not show that off-label use of rFVIIa reduces mortality or improves other direct outcomes. Thromboembolic events are increased by use of rFVIIa to treat spontaneous intracranial hemorrhage and in adult cardiac surgery.
The EHC program also offers a guide for clinicians, Utilization and Clinical Data on In-Hospital Off-Label Uses of Recombinant Factor VIIa. The course and guide can be found at
Effective Health Care Program
Current as of April 2011
Internet Citation: CME module offered on in-hospital off-label uses of recombinant factor VIIa: Research Activities, April 2011, No. 368.
April 2011. Agency for Healthcare Research and Quality, Rockville, MD. http://archive.ahrq.gov/news/newsletters/research-activities/apr11/0411RA39.html