AHRQ Announces Two New Funding Opportunities

Research Activities, January 2010, No. 353

Comparative Effectiveness Research to Optimize Prevention & Healthcare Management for the Complex Patient.

The Agency for Healthcare Research and Quality (AHRQ) under the American Recovery & Reinvestment Act of 2009 ("Recovery Act" or "ARRA"), Public Law 111-5, invites Exploratory/Developmental grant (R21) applications from organizations that aim to understand the comparative value of different strategies in the prevention and management of chronic illness in persons with specific constellations of co-morbid conditions. The objectives of this FOA are to:

  1. Support comparative effectiveness research to allow prioritization of evidence-based services (testing and treatment) for patients with multiple co-morbidities (including physical and mental conditions), and suggest appropriate adaptations (in timing and frequency) of recommended preventive and care management guidelines for these patients.
  2. Provide evidence to clarify how co-existing chronic conditions modify the safety or comparative value of proven treatments for chronic diseases and recommended preventive interventions.
  3. Provide evidence to refine chronic disease quality measures for complex and frail patients.

To achieve these objectives, expected research approaches include mathematical modeling, statistical modeling, or epidemiologic studies that may be based on data from population surveys, medical databases from electronic health records, and possibly insurance claims data.

AHRQ anticipates awarding 12-18 grants; the total amount expected to be awarded is $6,000,000. The project period duration and total cost budget limits vary by type of study proposed. This is a one-time-only solicitation, resubmissions are not permitted. Applications are due January 20, 2010. For more information, please go to: http://grants.nih.gov/grants/guide/rfa-files/RFA-HS-10-009.html.

Expansion of Research Capability to Study Comparative Effectiveness in Complex Patients (R24)

The Agency for Healthcare Research and Quality (AHRQ) under the American Recovery & Reinvestment Act of 2009 ("Recovery Act" or "ARRA"), Public Law 111-5, invites Exploratory/Developmental grant (R24) applications from organizations that propose to increase the capacity of high quality epidemiologic and comparative effectiveness research that will inform the health system of the future in its ability to care for people of all backgrounds with multiple chronic illnesses.

Mechanisms to build infrastructure include building or enhancing partnerships, datasets and methodologies that will improve the capacity to study, and the quality of studies, of patients with multiple chronic illnesses (referred to as Complex Patients). There are two main objectives for this Funding Opportunity Announcement: 1) The development of comparative effectiveness research infrastructure and 2) The performance of a related specific research project to demonstrate the potential of the new infrastructure.

  1. Develop infrastructure to facilitate the performance of comparative effectiveness research. Both data set development and research methods development are included in this FOA's consideration of infrastructure.� Only one is required in an application.
    1. Create or expand data sets to be used for research purposes.
    2. Develop and validate methods to improve the analytic methods for the study of important questions related to the management of complex patients.
  2. Performance of a specific research project. The research must take advantage of the specific methodological or other substantive thrust(s) of the infrastructure development being supported by the program.

AHRQ anticipates awarding 12 grants; the total amount expected to be awarded is $12,000,000. The project period duration is limited to two years. This is a one-time-only solicitation, resubmissions are not permitted. Applications due January 20, 2010. For more information, please go to: http://grants.nih.gov/grants/guide/rfa-files/RFA-HS-10-001.html.

Current as of January 2010
Internet Citation: AHRQ Announces Two New Funding Opportunities: Research Activities, January 2010, No. 353. January 2010. Agency for Healthcare Research and Quality, Rockville, MD. http://archive.ahrq.gov/news/newsletters/research-activities/jan10/0110RA27a.html