This information is for reference purposes only. It was current when produced and may now be outdated. Archive material is no longer maintained, and some links may not work. Persons with disabilities having difficulty accessing this information should contact us at: https://info.ahrq.gov. Let us know the nature of the problem, the Web address of what you want, and your contact information.
New clinician and consumer research summaries on treatment-resistant depression available
Research Activities, May 2012, No. 381
New clinician and consumer research summaries on nonpharmacologic therapies for treatment-resistant depression (TRD) are now available from the Effective Healthcare Program of the Agency for Healthcare Research and Quality (AHRQ). The summaries are based on a recently released research review, Nonpharmacologic Interventions for Treatment-Resistant Depression in Adults, which found insufficient evidence to evaluate whether nonpharmacologic treatments are effective for TRD. These new products summarize evidence on the effectiveness and efficacy of four non-pharmacologic treatments: electroconvulsive therapy, repetitive transcranial magnetic stimulation, vagus nerve stimulation, and cognitive behavioral therapy or interpersonal psychotherapy. Comparative clinical research on nonpharmacologic interventions for TRD is in its infancy. Many clinical questions about efficacy and effectiveness remain unanswered.
These materials and many others that explore the effectiveness and risks of treatment options for various conditions are available on AHRQ's Effective Health Care Program
Effective Health Care Program
Page last reviewed May 2012
Internet Citation: New clinician and consumer research summaries on treatment-resistant depression available: Research Activities, May 2012, No. 381.
May 2012. Agency for Healthcare Research and Quality, Rockville, MD. http://archive.ahrq.gov/news/newsletters/research-activities/may12/0512RA29.html
The information on this page is archived and provided for reference purposes only.