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Pediatric Terrorism and Disaster Preparedness

Public Health Emergency Preparedness

This resource was part of AHRQ's Public Health Emergency Preparedness program, which was discontinued on June 30, 2011, in a realignment of Federal efforts.

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Table 6.1. Biological Dosimetry Assays and Operational Parameters

Class of Biomarker Assay Time Window Operating Dose Window (Gy, acute photon-equivalent)
Prodromal signs and symptoms Onset of vomiting <12 hr 2-20
Hematological Depletion of peripheral blood lymphocytes <1.5 wk 2-8
Cytological Lymphocyte-metaphase spread dicentric < several monthsa 0.2-5
Lymphocyte-premature chromosome condensation <several monthsa 0.2-20

a Generally, blood is sampled 24 hours after radiation exposure for cytological chromosome aberration analysis of dose.

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