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Summaries of Independent Scientist (K) Awards

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Jenkins, Pamela

Institution: Dartmouth College
Grant Title: Improving Outcomes in Hypoplastic Left Heart Syndrome
Grant Number:  K02 HS00010
Duration: 5 years (2000-2005)
Total Award: $657,200

Project Description: This research had three main aims:

  1. Identify pre-operative and operative characteristics predictive of mortality in children with hypoplastic left heart syndrome (HLHS).
  2. Conduct functional testing of these pediatric patients.
  3. Conduct yearly survey of families with HLHS children.

Career Goals: Dr. Jenkins is an Assistant Professor in the Department of Pediatrics and Community and Family Medicine.  She received her M.D. from University of North Carolina at Chapel Hill School of Medicine.  She served her residency in Pediatrics at Dartmouth where she later received her Ph.D. in Outcomes Research.   Throughout her career, Dr. Jenkins has sought to improve the health outcomes of infants and children with congenital heart disease. 

Progress to Date: This award has been completed.  The publications list below highlights research findings.

Highlights and Specific Accomplishments:

  • Development of health perceptions assessment tool for children.
  • Professional societies: American Academy of Pediatrics.
  • Professional meetings: Society for Pediatric Research Conference; Seattle, American Heart Association national meeting, Orlando; and Cardiology 2004 meeting in Orlando; Society for Thoracic Surgery 2005 meeting, Tampa; American Academy of Thoracic Surgery meeting, 2005, San Francisco.

K-Generated Publications:

Jenkins PC, Flangan MF, Jenkins KJ, et al. Morbidities in patients with hypoplastic left heart syndrome. Pediatric Cardiology 2004. 25(1):3-10.

Jenkins PC.  sindrome del corazon izquierdo hipoplasico: supervivencia, riesgo de mortalidad y tendencias en el tratamiento [hypoplastic left heart syndrome: survival, mortality risk, and trends in management].  Journal Salud (i) Cienci.

Jenkins PC, Flanagan MF, Sargent JD, et al. A comparison of treatment strategies for hypoplastic left heart syndrome using decision analysis.  Journal of the American College of Cardiology 2001. (4)38:1181-87.

Jenkins PC, Flanagan MF, Jenkins KJ, et al. Survival analysis and risk factors for mortality in transplantation and staged surgery for hypoplastic left heart syndrome. Journal of the American College of Cardiology 2000. 36(4):1178-85.

Jenkins PC, Dickison A, Flanagan M. Cardiac inflammatory psudotumor: Rapid appearance in an infant with congenital heart disease. Pediatric Cardiology 1996. 17(6):399-401.

Mahle WT, Visconti, Freier C, Kanne Sm, Hamilton WG, Sharkey Am, Chinnock RE, Jenkins, KJ, Isquith PK, Burns TG, Jenkins PC. Relationship of surgical approach to neurodevelopment outcome in hypoplastic left heart syndrome. Pediatrics 2006. 117(1):e90-7.

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