This information is for reference purposes only. It was current when produced and may now be outdated. Archive material is no longer maintained, and some links may not work. Persons with disabilities having difficulty accessing this information should contact us at: https://info.ahrq.gov. Let us know the nature of the problem, the Web address of what you want, and your contact information.
Please go to www.ahrq.gov for current information.
Institution: Saint Louis University
Grant Title: Population
and Global Transition Assessments of HRQoL
Grant Number: K02 HS011635
Total Award: $484,700
Project Description: This project had five main
- Compare the three health related quality of life (HRQoL) measures in
Healthy People 2010.
- Establish benchmarks for categorizing score ranges for
- Identify change over time in these measures to evaluate
- Develop crosswalk score estimation methods between
these measures and other widely used measures.
- Model underlying
cognitive processes that patients employ when they assess their HRQol changes.
Career Goals: Dr. Wyrwich is Assistant
Professor of Research Methodology in the College of Public Service at Saint Louis University. She received her Ph.D. in Health Services Research also at Saint Louis University.
Progress to Date: This K02 has been
successfully completed. The research found that in general the HP2010 Leading
Health Indicators reflect expected changes in Healthy Days (HDs). Exceptions were seen with
the Behavioral Risk Factor Surveillance System (BRFSS) items binge drinking and having a firearm nearby.
K-Generated Publications: (selected)
Leidy NK, Wyrwich KW.
Bridging the gap: Using triangulation methodology to estimate minimal
clinically important differences (MCIDs). Journal of COPD 2005. 2:157-65.
Wyrwich, KW, Tierney WM, Babu AN, et al. A comparison of
clinically important differences in health-related quality of life for patients
with chronic lung disease, asthma, or heart disease. Health Services Research
Kroenke K, Wyrwich KW,
Tierney WM, et al. Physician-estimated disease severity in patients with
chronic heart or lung disease: A cross-sectional analysis. Health and Quality
of Life Outcomes 2006. 4:60.
Wu HS, Wyrwich KW.
Assessing fatigue in persons with cancer: Further validation of WuCancer
Fatigue Scale. Journal of Pain and Symptom Management 2006. 32(3):255-65.
Wyrwich KW, Tardino VM. Understanding global transition
assessments. Quality of Life Research 2006. 16(6):995-1004.
Wyrwich KW, Metz Sm, Kroenke K, et al. Interpreting quality of
life data: Methods of community consensus in asthma. Annals of Allergy, Asthma,
and Immunology 2006. 96(6).826-33.
Haughton K, Wyrwich KW,
Brownson RC, et al. Individual, social, environmental, and physical
environmental influences on physical activity among black and white adults: A
structural equation approach. Annals of Behavioral Medicine 2006. 31(1):36-44.
Boehmer T, Hoehner CM, Wyrwich
KW, et al. Correspondence between perceived and observed measures of
neighborhood environmental supports for physical activity. Journal of Physical
Activity and Health 2006. 3(1):22-36.
Return to Career Development Award Grants