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Human Growth Hormone Shows Promise in treating Cystic Fibrosis Symptoms

Electronic Newsletter, Issue 294

October 14, 2010

AHRQ News and Numbers

American men with prostate cancer were 25 percent less likely to die from the disease in 2006 than they were in 1999. [Source: Agency for Healthcare Research and Quality, .]

Today's Headlines

  1. Human growth hormone shows promise in treating cystic fibrosis symptoms
  2. New report proposes research agenda to transform health care based on principles of industrial system engineering
  3. New guide helps patients take care of themselves after hospital discharge
  4. Three new Medicaid-CHIP case studies now available
  5. AHRQ in the professional literature


1. Human Growth Hormone Shows Promise in treating Cystic Fibrosis Symptoms

A new AHRQ-funded report shows that human growth hormone can be used successfully to treat some symptoms of cystic fibrosis, but its impact on the disease itself remains unknown. The report, Effectiveness of Recombinant Human Growth Hormone (rhGH) in the Treatment of Patients with Cystic Fibrosis, finds that the use of human growth hormone increases height and weight, may improve lung functioning and may strengthen the bones of patients with cystic fibrosis. Researchers found evidence suggesting that human growth hormone therapy reduces the need for hospitalizations but could find no evidence that the therapy prolongs life or improves health-related quality of life. The use of human growth hormone was also found to raise blood sugar, which may over time lead to the development of diabetes in some patients. The report was produced by the University of Connecticut/Hartford Hospital Evidence-based Practice Center and the results were published online in Pediatrics. Select to read our press release and select to access the report.


2. New Report Proposes Research Agenda to Transform Health Care Based on Principles of Industrial System Engineering

A new report funded by AHRQ and the National Science Foundation found multiple opportunities to use industrial and systems engineering (ISyE) to help realize the goals of a new patient-centered health care system. Industrial and Systems Engineering and Health Care: Critical Areas of Research explores the critical areas of research at the ISyE and health care, with a special emphasis on the supportive role of health IT. Investing in ISyE research may help in creating a fundamentally better health care delivery system. Achieving such breakthrough change requires new ISyE methods specific to health care, and integrating knowledge production across countless demonstration projects and small research efforts. Innovation in health IT has the potential to support ISyE approaches to health systems design and evaluation. The full report provides a vision of the new health system and a detailed research and action agenda. Select to access the report (PDF File, Plugin Software Help).


3. New Guide Helps Patients Take Care of Themselves After Hospital Discharge

AHRQ has a new guide to help prepare patients to take care of themselves at home after they leave the hospital. The guide, Taking Care of Myself: A Guide for When I Leave the Hospital, helps patients by answering such questions as:

  • Whom do I contact if I have a problem?
  • What is my diagnosis?
  • What medicines have I been prescribed and when should I take them?
  • Which foods should I eat and what exercises should I do? Which should I avoid?
  • When are my next medical appointments, and what should I know about them?
  • What medicines can I safely take for headaches or other health problems?

Select to download a copy of the guide. Print copies of the bilingual guide (English/Spanish) are available by sending an E-mail to


4. Three New Medicaid-CHIP Case Studies Now Available

AHRQ has released three new case studies focused on the beneficial outcomes for Medicaid and CHIP agencies who implement Health IT and /or health information exchange to improve the quality of care for their beneficiaries. The new case studies are:

  • Leveraging Existing Leadership to Support Health IT and HIE: Lessons Learned from Minnesota's Medical Assistance Program.
  • Developing an Electronic Prescribing Incentive Program: Lessons Learned from New York Medicaid.
  • Developing a Universal Consent Form: Lessons Learned from Florida Medicaid.

Select to access these case studies and for more resources on health IT and HIE activities for Medicaid and CHIP.


5. AHRQ in the Professional Literature

We are providing the following hyperlinks to journal abstracts through PubMed® for your convenience. Unfortunately, some of you may not be able to access the abstracts because of firewalls or specific settings on your individual computer systems. If you are having problems, you should ask your technical support staff for possible remedies.

Hansen RA, Dusetzina SB, Song L, et al. Depression affects adherence measurement but not the effectiveness of an adherence intervention in heart failure patients. J Am Pharm Assoc 2009 Nov-Dec; 49(6):760-8. Select to access the abstract on PubMed.®

Anderson M, Cohrssen A, Klink K, et al. Are a speculum examination and wet mount always necessary for patients with vaginal symptoms? A pilot randomized controlled trial. J Am Board Fam Med 2009 Nov-Dec; 22(6):617-24. Select to access the abstract on PubMed.®

Holland ML, Kitzman H, Veazie P. The effects of stress on birth weight in low-income, unmarried black women. Womens Health Issues 2009 Nov-Dec; 19(6):390-7. Select to access the abstract on PubMed.®

Ghaferi AA, Birkmeyer JD, Dimick JB. Complications, failure to rescue, and mortality with major inpatient surgery in Medicare patients. Ann Surg 2009 Dec; 250(6):1029-34. Select to access the abstract on PubMed.®

Shaw SJ, Huebner C, Armin J, et al. The role of culture in health literacy and chronic disease screening and management. J Immigr Minor Health 2009 Dec; 11(6):460-7. Select to access the abstract on PubMed.®

Gibbons RD, Hur K, Brown CH, et al. Relationship between antiepileptic drugs and suicide attempts in patients with bipolar disorder. Arch Gen Psychiatry 2009 Dec; 66(12):1354-60. Select to access the abstract on PubMed.®

Contact Information

Please address comments and questions regarding the AHRQ Electronic Newsletter to Nancy Comfort at or (301) 427-1866.

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Page last reviewed October 2010
Internet Citation: Human Growth Hormone Shows Promise in treating Cystic Fibrosis Symptoms. October 2010. Agency for Healthcare Research and Quality, Rockville, MD.


The information on this page is archived and provided for reference purposes only.


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