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Pediatric Terrorism and Disaster Preparedness

Public Health Emergency Preparedness

This resource was part of AHRQ's Public Health Emergency Preparedness program, which was discontinued on June 30, 2011, in a realignment of Federal efforts.

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Table 4.5. Postexposure Prophylaxis for Anthrax

Patient Prophylactic Treatment
Adults (including pregnant women and immunocompromised people) Ciprofloxacin 500 mg, PO, BID 60 days or Doxycycline 100 mg, PO, BID 60 days
Children Ciprofloxacin 10-5 mg/kg, PO, BID 60 days (total daily dose not to exceed 1000 mg) or Doxycycline at:
  • >8 yr and >45 kg: 100 mg, PO, BID 60 days.
  • >8 yr and <45 kg: 2.2 mg/kg, PO, BID 60 days.
  • 8 yr or younger: 2.2 mg/kg, PO, BID 60 days.

Notes: BID = twice a day; PO = by mouth.

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